R. Kumanan et al. (2010) Screening of bark of Cinnamomum tamala (Lauraceae) by using á-amylase inhibition assay for anti-diabetic activity

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Screening of bark of Cinnamomum tamala (Lauraceae) by using á-amylase inhibition assay for anti-diabetic activity

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CONTRIBUTORS:

	Author:	R. Kumanan
	Author:	S. Manimaran
	Author:	Khan Saleemulla
	Author:	S.P. Dhanabal
	Author:	M.J. Nanjan

JOURNAL:

International Journal of Pharmaceutical and Biomedical Research, 01(02), 69 - 72.

YEAR:

2010

PUB TYPE:

Journal Article

SUBJECT(S):

Phytopharmacy, Phytomedicine, Pharmaceutical Sciences, Biomedical Sciences,

DISCIPLINE:

Pharmacy

HTTP:

http://www.pharmscidirect.com/Docs/IJPBR-2010-02-14.pdf

LANGUAGE:

English

PUB ID:

103-478-394 (Last edited on 2010/06/13 07:08:42 GMT-6)

SPONSOR(S):

ABSTRACT:
Diabetes is one of the major complications, the world faces today. Many reports suggest that Cinnamomum tamala (Lauraceae) has potent antidiabetic activity. The plant was selected based on their Ethno-pharmacological uses in traditional medicine. The present study focused on methanol and successive water extract of bark of Cinnamomum tamala was screened by using á-amylase inhibition assay for antidiabetic activity. The percentage inhibition values of methanol and successive water extract of bark of the Cinnamomum tamala were found 97.49% and 93.78% respectively. Similarly, IC50 values of methanol and successive water extract of the Cinnamomum tamala were found 1.80 and 5.53. The methanol extract of Cinnamomum tamala showed high potent activity than successive water extracts.

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