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Information Theory and Others for Steroids Separation

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CONTRIBUTORS:
  Author Carmen Elena STOENOIU
  Author Lorentz JÄNTSCHI (Technical University of Cluj-Napoca)
CONFERENCE TITLE:
  International Symposium on Organic Chemistry
CONF. LOCATION: None
YEAR: 2006
PUB TYPE: Conference Paper
SUBJECT(S): chemistry - analytical; chemistry - organic; informatics - models implementation; informatics - web programming; mathematics - modeling
DISCIPLINE: Chemistry
HTTP: http://lori.academicdirect.org/works/?id=100
LANGUAGE: English
PUB ID: 103-436-070 (Last edited on 2007/07/08 09:10:40 GMT-6)
SPONSOR(S):
 
ABSTRACT:
Chromatographic analysis, define as techniques used for the separation of a mixture of compounds by their distribution between two phases, was invented in 1901 by Russian botanist Mikhail Semyonovich Tsvet, during his research on plant pigments [1].
The chromatography is used in chemistry [2], biology [3], and medicine [4] as an analytical technique.
An original mathematical model for mobile phase optimization on High Performance Thin-Layer Chromatography was developed and its performances on two sets of steroids are presented.
The mobile phase optimization process proved to be able to provide accurate, precise and reproducible method useful in characterization and analysis of chromatographic parameters of studied steroids sets.
References
[1] E.M. Senchenkova. In: Gillispie (Ed.). Dictionary of scientific biography; Charles Scribner Sons: New York 13 (1976) 486.
[2] V.P. Papageorgiou, A. N. Assimopoulou, V. F. Samanidou and I. N. Papadoyannis. Curr. Org. Chem. 10 (2006) 583.
[3] T. Miyake and M. Yafuso. Plant. Species. Biol. 20 (2005) 201.
[4] L. Sharma, A. Desai and A. Sharma. Biochem. Mol. Biol. Educ. 34 (2006) 44-48.
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