Claudia CIMPOIU, Lorentz JÄNTSCHI and Teodor HODISAN (1999) A New Mathematical Model for the Optimization of the Mobile Phase Composition in HPTLC and the Comparision with Other Models

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A New Mathematical Model for the Optimization of the Mobile Phase Composition in HPTLC and the Comparision with Other Models

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CONTRIBUTORS:

	Author:	Claudia CIMPOIU
	Author:	Lorentz JÄNTSCHI (Technical University of Cluj-Napoca)
	Author:	Teodor HODISAN

JOURNAL:

Journal of liquid chromatography & related technologies, 22(10), 1429 - 1441.

YEAR:

1999

PUB TYPE:

Journal Article

SUBJECT(S):

chemistry - analytical; informatics - numerical optimization; mathematics - modeling

DISCIPLINE:

Chemistry

HTTP:

http://lori.academicdirect.org/works/?id=3

LANGUAGE:

English

PUB ID:

103-434-597 (Last edited on 2007/05/23 04:27:55 GMT-6)

SPONSOR(S):

ABSTRACT:
Mobile phase optimization is highly important in planar chromatography. Solvent selection based on experience and chromatographic intuition can be very time consuming when applied to complex mixtures. In these cases, more systematic strategies are needed. This paper presents a new mathematical model for the optimization of the mobile phase composition used for the separation of a mixture of 1,4-benzodiazepines and a comparison of this mathematical approach with other models.

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