Brembs et al. (2002) Operant Reward Learning in Aplysia: Neuronal Correlates and Mechanisms

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Operant Reward Learning in Aplysia: Neuronal Correlates and Mechanisms

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CONTRIBUTORS:

	Author:	Brembs, Björn (Freie Universität Berlin)
	Author:	Lorenzetti, Fred
	Author:	Reyes, Fredy
	Author:	Baxter, Douglas
	Author:	Byrne, John

JOURNAL:

Science magazine, 296(??), 1706 - 1709.

YEAR:

2002

PUB TYPE:

Journal Article

SUBJECT(S):

neurobiology, neuroscience, operant conditioning

DISCIPLINE:

Biology

HTTP:

http://bjoern.brembs.net/download.php?view.10

LANGUAGE:

English

PUB ID:

103-425-962 (Last edited on 2006/04/12 07:56:59 GMT-6)

SPONSOR(S):

ABSTRACT:
Operant conditioning is a form of associative learning through which an animal learns about the consequences of its behavior. Here we report an appetitive operant conditioning procedure in Aplysia that induces long-term memory. Biophysical changes that accompanied the memory were found in an identified neuron (cell B51) that is considered critical for the expression of behavior that was rewarded. Similar cellular changes in B51 were produced by contingent reinforcement of B51 with dopamine in a single-cell analogue of the operant procedure. These findings allow for the detailed analysis of the cellular and molecular processes underlying operant conditioning.

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