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Drosophila as a new model organism for the neurobiology of aggression?

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CONTRIBUTORS:
  Author Baier, Andrea
  Author Wittek, Britta
  Author Brembs, Björn (Freie Universität Berlin)
JOURNAL:
  The journal of experimental biology, 205(??), 1233 - 1240.
YEAR: 2002
PUB TYPE: Journal Article
SUBJECT(S): aggression, biology, neurobiology, neuroscience
DISCIPLINE: Biology
HTTP: http://bjoern.brembs.net/download.php?view.9
LANGUAGE: English
PUB ID: 103-425-961 (Last edited on 2006/04/12 07:24:26 GMT-6)
SPONSOR(S):
 
ABSTRACT:
We report here the effects of several neurobiological determinants on aggressive behaviour in the fruitfly Drosophila melanogaster. This study combines behavioural, transgenic, genetic and pharmacological techniques that are well established in the fruitfly, in the novel context of the neurobiology of aggression. We find that octopamine, dopamine and a region in the Drosophila brain called the mushroom bodies, have profound influence on the expression of aggressive behaviour. Serotonin had no effect. We conclude that Drosophila, with its advanced set of molecular tools and its behavioural richness, has the potential to develop into a new model organism for the study of the neurobiology of aggression.
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