Roberts and Smith (1999) Erythropoietin concentration and arterial haemoglobin saturation with supramaximal exercise

getCITED

Home Search Add Content Reports Help

Edit Publication | Edit Contributors | Delete Publication | Edit References | Edit Citations

Add to Bookstack | Show Bookstack | Change Bookstack

Erythropoietin concentration and arterial haemoglobin saturation with supramaximal exercise

Post a Comment

CONTRIBUTORS:

	Author:	Roberts, D.
	Author:	Smith, D. J.

JOURNAL:

Journal of Sports Sciences (JSS), 17(6), ?? - ??.

YEAR:

1999

PUB TYPE:

Journal Article

SUBJECT(S):

ERYTHROPOIETIN; ARTERY; HEMOGLOBIN; ATHLETE; ANOXEMIA; AEROBIC-CAPACITY; ANAEROBIC-CAPACITY

DISCIPLINE:

No discipline assigned

HTTP:

LANGUAGE:

English

PUB ID:

103-366-684 (Last edited on 2002/02/27 18:44:58 US/Mountain)

SPONSOR(S):

ABSTRACT:
The aim of this study was to determine if the hypoxaemic stimulus generated by intense exercise results in the physiological response of increased erythropoietin production. Twenty athletes exercised for 3 min at 109 plus/minus 2.8 % (mean plus/minus s) maximal oxygen consumption. Estimated oxyhaemoglobin saturation was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhaemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrations - as measured using the INCSTAR Epo-Trac radioimmunoassay - increased significantly by 28 plus/minus 9 % at 24 h post-exercise in 11 participants, who also had an arterial oxyhaemoglobin saturation less than or equal to 91 % (P < 0.05). Decrased ferritin levels and increased reticulocyte counts were observed at 96 h post-exercise. However, no significant changes in erythropoietin levels were observed in nine non-desaturating athletes and eight non-exercise controls. Good agreement was shown between arterial oxyhaemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement = -3.9 to 3.7 %). In conclusion, short supramaximal exercise can induce both hypoxaemia and increased erythropoietin levels in well-trained individuals. The decline of arterial hypoxaemia levels below 91 % during exercise appears to be necessary for the exercise-induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oximetry was found to be a valid predictor of percent arterial oxyhaemoglobin saturation during supramaximal exercise when percent estimated oxyhaemoglobin saturation greater than or equal to 86 %.

STATISTICS

Click on # to view
Citations		0
References		0
Comments		0
Quality		0/0.00
Interest		0/0.00
View(er)s		1/388

Quality
	N/A
High
	7
	6
	5
	4
	3
	2
	1
Low

Interest
	N/A
High
	7
	6
	5
	4
	3
	2
	1
Low

Prev | Next