Cellular immune activity in response to increased training of elite oarsmen prior to Olympic competition
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CONTRIBUTORS:
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JOURNAL:
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YEAR:
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1995
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PUB TYPE:
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Journal Article
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SUBJECT(S):
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ROWING; OVERTRAINING; TRAINING; ELITE-ATHLETE; MAN; PRE-COMPETITION; UNITED-KINGDOM; OLYMPIC-GAMES,-BARCELONA-1992; IMMUNE-SYSTEM; CREATININE
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DISCIPLINE:
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No discipline assigned
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HTTP:
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LANGUAGE:
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English
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PUB ID:
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103-366-473
(Last edited on
2002/02/27 18:45:01 US/Mountain)
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SPONSOR(S):
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ABSTRACT:
This study investigated the changes in urinary neopterin, a biochemical marker of cellular immune activity, in elite male rowers undertaking a progressive increase in training prior to Olympic competition. Twenty-seven male rowers of the 1992 Great Britain team provided daily urine samples for a 4-week period of training that included 17 days of altitude training and 10 days of heat acclimatization. The mean (plus/minus S.D.) ratio of neopterin/creatinine in urine increased from pre-training values of 135 plus/minus 32 to a peak of 219 plus/minus 121 umol neopterin per mol creatinine on day 19 of training. Changes in the ratio of neopterin/creatinine with training were found to be transient and highly variable between subjects, ranging from no change to peak values five-fold greater than baseline. On the basis of the in vivo measurement of cell-mediated immunity employed in this study, we conclude that elite athletes engaged in high-intensity training prior to competition show either no change or a moderate increase in cellular immune activation.
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