Effects of acute hypoxia on the VO2max of trained and untrained subjects
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CONTRIBUTORS:
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JOURNAL:
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YEAR:
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1993
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PUB TYPE:
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Journal Article
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SUBJECT(S):
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ELITE-ATHLETE; NON-ATHLETE; COMPARATIVE-STUDY; ADAPTATION; AEROBIC-CAPACITY; SIMULATION; ALTITUDE
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DISCIPLINE:
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No discipline assigned
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HTTP:
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LANGUAGE:
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English
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PUB ID:
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103-366-375
(Last edited on
2002/02/27 18:45:01 US/Mountain)
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SPONSOR(S):
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ABSTRACT:
The purpose of this study was to compare the responses of highly trained (TR) and untrained (UT) subjects' maximal oxygen uptake (VO2max) while breathing a hypoxic gas mixture. Two groups of healthy volunteers were recruited: (1) trained subjects (n=8), VO2max=67.2 plus/minus 4.0 kg-1min-1; (2) untrained subjects (n=8), VO2max=45.4 plus/minus 5.5 ml kg-1 min-1. Both groups were administered maximal cycle ergometer tests under hypoxic (13 percent O2, 87 percent N2) and normoxic conditions (21 percent O2, 79 percent N2). A pulse oximeter (Ohmeda 3700) was used to estimate arterial haemoglobin saturation (SpO2). The trained group had lower values for SpO2 at maximal exercise (TR=67.0 plus/minus 7.1 percent, UT=77.5 plus/minus 9.0 percent) and greater reductions in VO2max (TR=-26.0 plus/minus 2.3 percent; UT=-14.9 plus/minus 5.1 percent) under hypoxic conditions. The percent change in VO2max while breathing the hypoxic gas mixture was linearly correlated with the subjects' normoxic VO2max (ml kg-1min-1; r=-0.91). These results indicate that highly trained subjects experience greater percent decrements in SPO2 and VO2 max while breathing a moderately hypoxic gas mixture compared to untrained subjects, and may explain some of the variable decrease observed when VO2max is measured at simulated altitude.
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